Imagining liver histologically,consist of...
- Epithelial hepatocytes arranged in cords
- This cords are seperated from eact other by vascular sinusoids(4 structures in body with sinusoids are endocrine glands,liver,spleen,lymph nodes)
- Vascular or hepatic sinusoids are lined by fenestrated endothelium
- Space of disse - space between fenestrated endothelium and hepatocyte is called space of disse
- Blood from sinusoids pass easily through fenestrated endothelium into space of disse.Thus we can say hepatocytes are in direct contact with blood
- Kupffer cells -¤This are macrophages in liver¤star shaped,branched cytoplasm,large nuclei
- Liver lobule - portion of liver tissue drained by single central vein(br of hepatic vein),hexagonal structure on crossection
- Liver acini - potion of liver tissue supplied by single central artery(br of hepatic artery),forms diamond shaped triangular structure,is functional unit of liver
- Liver has dual blood supply - 1) all blood from spleen and intestine is drained via portal vein to liver 2) oxygenated blood by hepatic artery
